Homework grill!?

What is the most predictable outcome of administering a highly bound protein drug to an individual beside hypoalbuminemia?
(a) inability to metabolize the drug
(b) greatly prolonged plasma half-life
(c) greater than expected response to the drug
(D) inability to excrete the drug
I have looked everywhere but can't find answer, please assistance!! Thanks in finance
Drug bound to protein is inactive (not "bioavailable"). With hypoalbuminemia, more free drug would be available to receptors. (A) is incorrect (the liver would still be capable of metabolize the drug); (B) is similarly incorrect (the plasma t1/2 would be *reduced* as the rate of metabolism of the drug would be increased, diminishing at a higher rate, the amount not here in the plasma); (D) make no sense (low plasma protein would not make it such that the drug could not be conjugated (in the liver) and excreted by kidneys).
(C) is the solitary correct answer, i.e. with more influential drug, you would expect an exaggerated response with the direction of a highly protein-bound drug.
Albumin is a principal protein in the human body, making up nearly 60% of total human plasma protein by mass. Many hormones, drugs, and other molecules are mostly bound to albumin in the bloodstream and must be released past becoming biologically active.
Hence the answer is A.(presumption)
Please transcribe that I am not a medical professional.
medicine and vigour guarantee correctness , is for informational purposes only direction or treatment for any medical conditions.

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